Distonia de Segawa responsível a canabidiol: A propósito de um caso

Abstract

A epilepsia e a distonia responsiva a levodopa são entidades neurológicas que têm suas terapêuticas definidas, a priori, com uso de anti-epiléticos e levodopa. O uso de derivados de cannabis, principalmente canabidiol, vem se mostrando benéfico em diversas desordens neurológicas. Este presente relato descreve a história de um jovem paciente com epilepsia associado a distonia responsiva à levodopa, associação rara, que respondeu de maneira notável a terapêutica com o óleo de cannabis rico em CBD, algo até então inédito na literatura.

Segawa dystonia is a neurological disorder, usually with higher incidence in the first and second decade of life, mostly in females. Its clinical presentation is due to initial dystonia of the lower limbs, which may progresses to generalized if inadequately treated. It has a good response to the continuous use of levodopa, in low doses. The use of cannabis-derived drugs has grown in the past years, as it has shown promise in the treatment of epilepsy refractory to conventional pharmacology. One of its derivatives, CBD full spectrum cannabis oil proved to be beneficial in the treatment of Segawa's Disease, that until now had not been discussed in bibliographic research.